Detalhe da pesquisa
1.
Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.
Cell
; 150(5): 895-908, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22939619
2.
RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression.
Nucleic Acids Res
; 41(18): 8788-801, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23887934
3.
ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.
Nucleic Acids Res
; 41(20): 9570-83, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935115
4.
Antisense and antigene inhibition of gene expression by cell-permeable oligonucleotide-oligospermine conjugates.
J Am Chem Soc
; 133(22): 8404-7, 2011 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21539318
5.
Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.
Biochemistry
; 49(47): 10166-78, 2010 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21028906
6.
Nuclear and Cytoplasmatic Quantification of Unconjugated, Label-Free Locked Nucleic Acid Oligonucleotides.
Nucleic Acid Ther
; 30(1): 4-13, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31618108
7.
Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA.
Mol Ther Nucleic Acids
; 8: 158-168, 2017 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918018
8.
Single-Stranded Silencing RNAs: Hit Rate and Chemical Modification.
Nucleic Acid Ther
; 26(4): 216-22, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27123752
9.
Generation of novel hybrid aptamer-molecularly imprinted polymeric nanoparticles.
Adv Mater
; 27(4): 750-8, 2015 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25413444
10.
Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.
Nucleic Acid Ther
; 24(3): 199-209, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24694346